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NEWS & TOPICS

Chem. Pharm. Bull. Vol. 72 No. 7

2024/09/02

Cover
Structure-Activity Relationship Study of CYM51010, an Agonist for the μ-δ Opioid Receptor Heterodimer
pp. 711-730

Graphical Abstracts


Current Topics - Frontiers in Alzheimer's and Dementia Research

Foreword

Ken-ichi Kusakabe


Current Topics: Review

Anti-amyloid-β Antibodies and Anti-tau Therapies for Alzheimer's Disease: Recent Advances and Perspectives

Naoyuki Suzuki, Takuya Hatta, Mana Ito, and Ken-ichi Kusakabe

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Clinical Pipelines for Alzheimer's Disease Psychosis and Agitation

Takuya Oguma and Kohei Jino

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Neuroimmune Dysfunction in Alzheimer's Disease and Other Forms of Dementia

Takuya Yamane, Takeshi Yoshioka, and Yusuke Shimo

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Epigenetic Inhibitors as Alzheimer's Disease Therapeutic Agents

Yasunobu Yamashita, Yukihiro Itoh, Yuri Takada, and Takayoshi Suzuki

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Current Topics: Regular Article

Identification of Proteolysis Targeting Chimeras (PROTACs) for Lysine Demethylase 5 and Their Neurite Outgrowth-Promoting Activity

Tetsuya Iida, Yukihiro Itoh, Yukari Takahashi, Yuka Miyake, Farzad Zamani, Yasunobu Yamashita, Yuri Takada, Toshiki Akiyama, Jun Ibaraki, Kyoka Okuda, Yuto Tokuda, Tomoka Nishimura, Koto Hidaka, Hiiro Mori, Makoto Oba, and Takayoshi Suzuki

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Regular Article

Spectral and HPLC Analyses of Synthesized Butin and Butein

Takashi Kamei, Jun Miyazaki, Ryoga Hori, Hiroaki Saito, Tatsuo Takahashi, Ken-ichi Shinohara, Masakazu Miura, and Hirokazu Suzuki

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The Application of Microsampling Disks in Circular Dichroism Spectroscopy for Peptide and Nucleic Acid Drugs

Genichiro Tsuji, Takashi Misawa, and Yosuke Demizu

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Note

Estimation for Raw Material Plants of a Henna Product Using LC-High Resolution MS and Multivariate Analysis

Naohiro Oshima, Maiko Tahara, Tsuyoshi Kawakami, Akiko Yagami, Takumi Akiyama, Nahoko Uchiyama, and Yoshiaki Ikarashi

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Regular Article

Galangin Promotes Tendon Repair Mediated by Tendon-Derived Stem Cells through Activating the TGF-β1/Smad3 Signaling Pathway

Xiongwei Deng, Qiang Li, Haitao Yuan, Hejun Hu, and Shaoyong Fan

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Note

Continuous Monitoring of Pseudopolymorphic Transition in Ezetimibe Using T1 Relaxation with Time-Domain NMR

Takashi Ono, Kotaro Okada, Misaki Kaga, Hidekatsu Eto, Shungo Kumada, Nobuyuki Wakui, and Yoshinori Onuki

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Regular Article

Preparation and Evaluation of Clarithromycin Taste-Masking Dry Suspension Using Hot Melt Extrusion Based on Solid Dispersion Technology

Tianao Zhang, Min Yu, Yong Fan, Lingyang Wang, Lu Yuan, and Yong Sun

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Note

Total Synthesis of Dinorsesquiterpenoid Oxyphyllin A/Belchinoid A

Koichiro Ota, Naoya Kashima, Haruhiko Fukaya, Shinnosuke Okazaki, and Hiroaki Miyaoka

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Regular Article

Evaluation of STAT3 Inhibition by Cancer Chemopreventive Trichothecenes Derived from Metabolites of Trichothecium roseum

Mitsuaki Yamashita, Akari Nakanishi, Chiehming Chang, Kosei Tsurushima, Kiyoshige Nakamoto, and Akira Iida

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Two Preparation Methods for Peptide Thioester Containing Tyr(SO3H) Residue(s) without the Use of Protecting Group for Sulfate Moiety

Yumi Sekigawa, Shinichi Asada, Yurie Ichikawa, Kazuaki Tsubokawa, Shoh Watanabe, Shinobu Honzawa, and Kouki Kitagawa

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Structure-Activity Relationship Study of CYM51010, an Agonist for the µ-δ Opioid Receptor Heterodimer

Ayaka Watanabe, Shuma Yamada, Haruka Yoshida, Miku Inagaki, Nao Atsumi, Aoba Matsushima, Naoki Takahashi, Naoto Ishibashi, Takumi Ogino, Ryoto Someya, Ai Taguchi, Ryo Kagaya, Karin Ashizawa, Hinako Mendori, Yusuke Karasawa, Kaori Ohshima, Akinobu Yokoyama, Miki Nonaka, Kanako Miyano, Fumika Karaki, Shigeto Hirayama, Kennosuke Itoh, Yasuhito Uezono, and Hideaki Fujii

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