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NEWS & TOPICS

Biol. Pharm. Bull. Vol. 46 No. 12

2023/12/01

Cover
Innovative System for Delivering Nucleic Acids/Genes Based on Controlled Intracellular Trafficking as Well as Controlled Biodistribution for Nanomedicines
pp. 1648-1660

Graphical Abstracts


Review

Innovative System for Delivering Nucleic Acids/Genes Based on Controlled Intracellular Trafficking as Well as Controlled Biodistribution for Nanomedicines

Hideyoshi Harashima




Communication to the Editor

Framework-Directed Amino-Acid Insertions Generated over 55-Fold Affinity-Matured Antibody Fragments That Enabled Sensitive Luminescent Immunoassays of Cortisol

Yuki Kiguchi, Izumi Morita, Kouya Yamaki, Shigehiko Takegami, and Norihiro Kobayashi




Regular Articles

Assessment of Biological Activities, Acute and Sub-chronic Toxicity of Liang (Gnetum gnemon var. tenerum) Leaves Powder, a Natural Product

Anunya Suksanga, Sunisa Siripongvutikorn, Rattana Leelawattana, Chutha Takahashi Yupanqui, and Ayodeji Oluwafemi Idowu



MMethod for Preparing Recombinant Galectin-2 Protein without Escherichia coli-Specific Post-translational Modifications

Mayumi Tamura, Norihiko Fujii, Tomoharu Takeuchi, Masato Tsuyuguchi, Takashi Tanikawa, Saori Oka, Tomomi Hatanaka, Seishi Kishimoto, Ryuichi Kato, and Yoichiro Arata

Effects of Long-Term High-Ergosterol Intake on the Cholesterol and Vitamin D Biosynthetic Pathways of Rats Fed a High-Fat and High-Sucrose Diet

Naoko Kuwabara, Shinji Sato, and Saori Nakagawa

Evaluation of the Influence of Genetic and Environmental Factors on the Ephedrine Alkaloids Content of Ephedra sinica

Hajime Hiyama, Yosuke Yoshioka, and Ryo Ohsawa

Characterization of Potentially Inappropriate Medications That Need Special Attention in the Elderly with Dementia by Analyzing Pharmacy Claims Data

Yoshihito Kasanami, Takashi Yamamoto, Tomoyoshi Miyamoto, Sumio Matzno, Mikio Sakakibara, Masahiro Iwaki, and Atsufumi Kawabata

Bifidobacterium animalis subsp. lactis LKM512 Alleviates Inflammatory Bowel Disease in Larval Zebrafish by Reshaping Microbiota

Yuru Yang, Haimei Du, Yuxiang Pan, Ping Gong, Yi Yang, Fan Wu, Dixin Pan, Weihao Xie, Zhengwei Fu, and Yinhua Ni


Efficacy of Naldemedine on Intestinal Hypomotility and Adhesions in Rodent Models of Postoperative Ileus

Yuki Azuma, Katsumi Koike, Hiroki Chiba, Aki Mitamura, Hiroki Tsuji, Sachiko Kawasaki, Takaaki Yokota, Toshiyuki Kanemasa, Yasuhide Morioka, Tsutomu Suzuki, and Masahide Fujita



Exploring Cell-Penetrating Peptides as Penetration Enhancers in Eye Drop Formulations Using a Reconstructed Human Corneal Epithelial Model

Ryo Morofuji, Hiroshi Enomoto, Takahiro Honda, Yuki Oyama, Reiji Ishida, Kazuhiro Kudo, and Komei Okabe



Effect of Ceftriaxone Dosage and Albumin-Bilirubin Score on the Risk of Ceftriaxone-Induced Liver Injury

Hayahide Ooi, Yuki Asai, Yoshiki Koriyama, and Masaaki Takahashi



Identification of a DBA/2 Mouse Sub-strain as a Model for Pseudoxanthoma Elasticum-Like Tissue Calcification

Shota Morikane, Koichi Ishida, Tetsuya Taniguchi, Naoki Ashizawa, Masaya Matsubayashi, Naoki Kurita, Seiichi Kobashi, and Takashi Iwanaga



The Effects of Jabara Juice on the Intestinal Permeation of Fexofenadine

Hongye Han, Takeshi Akiyoshi, Tokio Morita, Toshiaki Tsuchitani, Momoko Nabeta, Kodai Yajima, Ayuko Imaoka, and Hisakazu Ohtani



Arid5a/IL-6/PAI-1 Signaling Is Involved in the Pathogenesis of Lipopolysaccharide-Induced Kidney Injury

Koki Tanaka, Hiroki Harada, Hiroyasu Kamuro, Hibiki Sakai, Ayaha Yamamoto, Masashi Tomimatsu, Akari Ikeda, Renya Chosokabe, Shota Tanaka, Yoshiaki Okada, Yasushi Fujio, and Masanori Obana



Potential Lipolytic Effect of Panduratin A Loaded Microspicule Serum as a Transdermal Delivery Approach for Subcutaneous Fat Reduction

Kusuma Jitsaeng, Sureewan Duangjit, Phaijit Sritananuwat, Kritsanaporn Tansathien, Praneet Opanasopit, and Worranan Rangsimawong



TNF-α Mediated the Disruption of Hepatic Tight Junction Expression in Blood-Biliary Barrier of Colitis via Downregulating PI3K/AKT Signaling Pathway

Xian-sen Jiang, Bi-le Fu, Xin-xin Yang, and Hong-yan Qin



Identification of the Acidification Mechanism of the Optimal pH for RNase He1

Katsuki Takebe, Mamoru Suzuki, Takeshi Sangawa, Naomi Motoyoshi, Tadashi Itagaki, Kana Kashima, Narikazu Uzawa, and Hiroko Kobayashi



Kuanoniamine C Suppresses Adipogenesis and White Adipose Tissue Expansion by Modulating Mitochondrial Function

Shoma Oki, Sou Kageyama, Kayo Machihara, and Takushi Namba



Fentanyl Promoted the Growth of Placenta Trophoblast Cells through Regulating the METTL14 Mediated CCL5 Levels

Yongyan Chen, Gaihua Lv, Xiuping Du, Fei Yang, and Zhiliang Zhao



Application Site of Transdermal Scopolamine Influences Efficacy and Drug Concentration in Salivary Glands in Rats

Natsuko Ishida, Yoshitaka Oshima, Ayano Katsura, Rikako Imamura, Hiroshi Arakawa, Tsutomu Shimada, Satoshi Mizuno, Yoshimichi Sai, Yukio Suga, and Ryo Matsushita



Effects of Yinzhihuang on Alleviating Cyclosporine A-Induced Cholestatic Liver Injury via Farnesoid X Receptor-Mediated Regulation of Transporters and Enzymes in Vitro and in Vivo

Yanjie Qin, Jingxuan Tan, Xuemei Han, Nanxi Wang, Xuejia Zhai, and Yongning Lu



The Plasma Membrane Polarity Is Higher in the Neuronal Growth Cone than in the Cell Body of Hippocampal and Cerebellar Granule Neurons

Shintaro Oya, Katsunari Korogi, Takao Kohno, Hitomi Tsuiji, Dmytro I. Danylchuk, Andrey S. Klymchenko, Yosuke Niko, and Mitsuharu Hattori




Notes

A Retrospective Observational Study of Factors Affecting the Efficacy of Concurrent Prescription of Naldemedine for Opioid-Induced Constipation Caused by Oxycodone Tablets

Masami Yamada, Yumi Jimaru, Sari Torii, Naoko Mitsuba, and Kazushige Takahashi



Analysis of Risk Factors for Developing Tuberculosis in Patients Who Received Prophylactic Latent Tuberculosis Infection Treatment with Experience of Biologic Medications

Marina Itagaki, Osamu Iketani, Yuki Enoki, Victor Tuan Giam Chuang, Kazuaki Taguchi, Shunsuke Uno, Sho Uchida, Ho Namkoong, Yoshifumi Uwamino, Yaoko Takano, Naoki Hasegawa, and Kazuaki Matsumoto



Trends in Implementation of Loading Dose of Voriconazole from 2010 to 2019 and Influencing Factors of Loading Dose Based on a Japanese Administrative Claim Database: A Retrospective Cohort Study

Ryo Inose, Ryota Goto, Misato Shimoki, Norio Ohmagari, and Yuichi Muraki



Removal of Soluble ACE2 in VeroE6 Cells by 17β-Estradiol Reduces SARS-CoV-2 Infectivity

Yuta Kyosei, Teruki Yoshimura, and Etsuro Ito





Role of Rho Kinase in Regulating Arterial Stiffness in Anesthetized Rabbits

Akira Takahara, Manami Matsumoto, Akira Sato, Shuto Inose, Megumi Aimoto, and Yoshinobu Nagasawa




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