Sent Date: July 1, 2022

The latest issue of Biol. Pharm. Bull. (BPB)

Vol. 45 No. 7

Review

Health Effects and Safety Assurance of Nanoparticles in Vulnerable Generations

Kazuma Higashisaka

Current Topics - Present and Future of Therapeutic Drug Monitoring in New Fields

Foreword

Hiroki Itoh

Current Topics: Reviews

Dose Individualization of Oral Multi-Kinase Inhibitors for the Implementation of Therapeutic Drug Monitoring

Satoshi Noda, Shin-ya Morita, and Tomohiro Terada

Target Therapeutic Ranges of Anti-MRSA Drugs, Linezolid, Tedizolid and Daptomycin, and the Necessity of TDM

Kazuaki Matsumoto, Masaru Samura, Sho Tashiro, Shino Shishido, Reika Saiki, Wataru Takemura, Kana Misawa, Xiaoxi Liu, Yuki Enoki, and Kazuaki Taguchi

New Insight Concerning Therapeutic Drug Monitoring--The Importance of the Concept of Psychonephrology--

Mai Hashimoto, Hitoshi Maeda, Kentaro Oniki, Norio Yasui-Furukori, Hiroshi Watanabe, Junji Saruwatari, and Daisuke Kadowaki

Therapeutic Drug Monitoring of Antibody Drugs

Atsushi Yonezawa

Communications to the Editor

Quiescent B Cells Acquire Sensitivity to Cell Cycle Arresting Agents by B Cell Receptor Stimulation

Takanatsu Hosokawa, Shinya Tanaka, Takeshi Mori, Yoshihiro Baba, and Yoshiki Katayama

More than 370-Fold Increase in Antibody Affinity to Estradiol-17β by Exploring Substitutions in the V_H-CDR3

Izumi Morita, Yuki Kiguchi, Saya Nakamura, Ayano Yoshida, Haruna Kubo, Momo Ishida, Hiroyuki Oyama, and Norihiro Kobayashi

Regular Articles

Evaluation of a Webinar for Pharmacists Learning Basic Clinical-Oncology during COVID-19 Pandemic in Japan

Hideyuki Terazono, Masami Tsuchiya, Yosuke Maki, Naoki Yoshikawa, Yosuke Kawahara, Keiko Nishimura, Keisuke Shinohara, Daisuke Ogawa, Riho Mori, Yoshihiro Iwamoto, Fumio Itagaki, Hiroyuki Masuko, Masahito Yonemura, and Mayako Uchida

Saikosaponin A Inhibits Growth of Human Bladder Carcinoma T24 and 5637 Cells Both in Vitro and in Vivo

Qian Zhou, Wei-Wei Wu, Chun-Lei Yu, Peng Wang, Xiao-Qian Wen, Bi-Ling Chen, Ying Zhang, Min Zhuang, Meng-Ying Zhang, Hao-Yuan Zhang, and Jian-Wu Zhang

Enhanced Type I Collagen Synthesis in Fibroblasts by Dermal Stem/Progenitor Cell-Derived Exosomes

Ayumi Sanada, Takaaki Yamada, Seiji Hasegawa, Yoshie Ishii, Yuichi Hasebe, Yohei Iwata, Masaru Arima, Kazumitsu Sugiura, and Hirohiko Akamatsu

Hospital-Wide Surveillance of Fracture Risk Assessment by Both FRAX and Medication Patterns in Acute Care Hospital

Takao Tobe, Misaki Kubo, Takahiro Toda, Mitsuhiro Morita, Mika Watanabe, Shigeki Yamada, Atsushi Suzuki, and Takahiro Hayashi

Juzentaihoto Suppresses Muscle Atrophy in KKAy Mice

Tomoaki Ishida, Kohei Jobu, Shumpei Morisawa, Kei Kawada, Saburo Yoshioka, and Mitsuhiko Miyamura

Difference in Cost-Effectiveness between First-Line and Third-Line or Later Nivolumab Therapy in Patients with HER2-Negative, Unresectable, Advanced or Recurrent Gastric or Gastro-Esophageal Junction Cancer in Japan

Munenobu Kashiwa and Ryo Matsushita

An Indirect Competitive Enzyme-Linked Immunosorbent Assay for the Determination of Brigatinib and Gilteritinib Using a Specific Polyclonal Antibody

Hiroto Kataoka, Tetsuya Saita, Asuki Oka, Momoka Yamada, and Masashi Shin

Increased 20S Proteasome Expression and the Effect of Bortezomib during Cisplatin-Induced Muscle Atrophy

Hiroyasu Sakai, Yujie Zhou, Yu Miyauchi, Yuta Suzuki, Yohei Ikeno, Risako Kon, Nobutomo Ikarashi, Yoshihiko Chiba, Tomoo Hosoe, and Junzo Kamei

A New Method to Visualize the Internal Morphology of Crude Drugs Using High-Resolution X-Ray Computed Tomography

Hiroko Tokumoto, Eiichi Yamamoto, Takashi Hakamatsuka, and Nahoko Uchiyama

Development of a Nanocarrier-Based Splenic B Cell-Targeting System for Loading Antigens in Vitro

Yoshino Kawaguchi, Taro Shimizu, Hidenori Ando, Yu Ishima, and Tatsuhiro Ishida

Skin Dryness Induced in the KK-Ay/TaJcl Type 2 Diabetes Mouse Model Deteriorates Following Dapagliflozin Administration

Tsuneki Horikawa, Keiichi Hiramoto, Shota Tanaka, and Kazuya Ooi

Proarrhythmia Risk Assessment Using Electro-Mechanical Window in Human iPS Cell-Derived Cardiomyocytes

Shota Yanagida, Ayano Satsuka, Sayo Hayashi, Atsushi Ono, and Yasunari Kanda

Notes

Population Pharmacokinetic Model of Amiodarone and N-Desethylamiodarone Focusing on Glucocorticoid and Inflammation

Toshinori Hirai, Hidefumi Kasai, Masahiro Takahashi, Satomi Uchida, Naoko Akai, Kazuhiko Hanada, Toshimasa Itoh, and Takuya Iwamoto

Study on Catalpol Content in Rehmannia glutinosa Root, an Important Ingredient in Kampo Prescriptions

Yuting Huang, Hirokazu Ando, Mai Tsujino, Kazuki Yoshihara, Li Zhang, and Yohei Sasaki

Mesenchymal Stem Cells Promote IL-6 Secretion and Suppress the Gene Expression of Proinflammatory Cytokines in Contractile C2C12 Myotubes

Yusuke Kono, Hiroki Kajita, Takuya Okada, Rina Nakagawa, Takuya Fujita, and Satoshi Konishi

Biotransformation of Morphinone and Its Glutathione Adduct Derived from Morphine by Anaerobic Gut Microbes in Guinea Pigs

Yoshito Kumagai