Sent Date: March 1, 2022

The latest issue of Biol. Pharm. Bull. (BPB)

Vol. 45 No. 3

Communication to the Editor

Effects of Disodium Cromoglycate Treatment in the Early Stage of Diabetic Nephropathy: Focus on Collagen Deposition

Mateus Jacinto da Luz, Victor Augusto Alves da Costa, Ana Paula Coelho Balbi, and Luiz Borges Bispo-da-Silva

Regular Articles

ETV6 Regulates Hemin-Induced Erythroid Differentiation of K562 Cells through Mediating the Raf/MEK/ERK Pathway

Zhaopeng Li, Ming-Zhong Sun, Xinxin Lv, Chunmei Guo, and Shuqing Liu

Vitexin Attenuates Non-alcoholic Fatty Liver Disease Lipid Accumulation in High Fat-Diet Fed Mice by Activating Autophagy and Reducing Endoplasmic Reticulum Stress in Liver

Yan Jiang, Qiming Gong, Yuanxun Gong, Chenyi Zhuo, Jinmei Huang, and Qianli Tang

Cold-Restraint Stress-Induced Ultrasonic Vocalization as a Novel Tool to Measure Anxiety in Mice

Tsugumi Yamauchi, Toshinori Yoshioka, Daisuke Yamada, Takumi Hamano, Misaki Ohashi, Maki Matsumoto, Keita Iio, Maika Ikeda, Masato Kamei, Takaya Otsuki, Yasuo Sato, Kyoko Nii, Masashi Suzuki, Hiroko Ichikawa, Hiroshi Nagase, Satoshi Iriyama, Kazumi Yoshizawa, Shoichi Nishino, Satoru Miyazaki, and Akiyoshi Saitoh

Troglitazone-Induced Autophagic Cytotoxicity in Lung Adenocarcinoma Cell Lines

Yoshie Tsujiya, Ai Hasegawa, Motohiro Yamamori, and Noboru Okamura

Improved Refolding of a Human IgG1 Fc (CH2-CH3) Scaffold from Its Inclusion Body in E. coli by Alkaline Solubilization

Show Ishikawa, Haruna Ishikawa, and Atsushi Sato

Development of SCAR Markers to Identify Medicinal Cultivars of Paeonia lactiflora

Yuina Yoshie, Hirokazu Ando, Takayuki Tamura, Kozo Fukuda, Motoko Igarashi, Atsuyuki Hishida, Nobuo Kawahara, and Yohei Sasaki

3′,4′,7-Trihydroxyflavone Downregulates NO Production in LPS- or IFN-γ-Activated MG6 Microglial Cells by Attenuating the JNK-STAT1 Pathway

Tatsuhiro Akaishi, Shohei Yamamoto, and Kazuho Abe

Synergistic Effect of Baculovirus-Mediated Endostatin and Angiostatin Combined with Gemcitabine in Hepatocellular Carcinoma

Yonggan Ji, Hongli Fan, Mengmeng Yang, Changcai Bai, Wen Yang, and Zhisheng Wang

Evaluation of Platinum Anticancer Drug-Induced Kidney Injury in Primary Culture of Rat Kidney Tissue Slices by Using Gas-Permeable Plates

Hiroshi Arakawa, Yurika Nagao, Shiho Nedachi, Yoshiyuki Shirasaka, and Ikumi Tamai

Infliximab Treatment Persistence among Japanese Patients with Chronic Inflammatory Diseases: A Retrospective Japanese Claims Data Study

Sho Masui, Atsushi Yonezawa, Kenji Momo, Shunsaku Nakagawa, Kotaro Itohara, Satoshi Imai, Takayuki Nakagawa, and Kazuo Matsubara

Risk Factors of Proteinuria in Patients with Hepatocellular Carcinoma Receiving Lenvatinib

Hiroaki Ikesue, Haruna Yamamoto, Masaki Hirabatake, Tohru Hashida, Hobyung Chung, Tetsuro Inokuma, and Nobuyuki Muroi

Betulin Attenuates TGF-β1- and PGE₂-Mediated Inhibition of NK Cell Activity to Suppress Tumor Progression and Metastasis in Mice

Masaru Ogasawara, Shino Yamasaki-Yashiki, Masahiro Hamada, Tomomi Yamaguchi-Miyamoto, Toru Kawasuji, Hiroe Honda, Tsutomu Yanagibashi, Masashi Ikutani, Yasuharu Watanabe, Ryota Fujimoto, Takayuki Matsunaga, Noriyuki Nakajima, Yoshinori Nagai, and Kiyoshi Takatsu

Activation of Host Immune Cells by Probiotic-Derived Extracellular Vesicles via TLR2-Mediated Signaling Pathways

Masaki Morishita, Risa Sagayama, Yuta Yamawaki, Marina Yamaguchi, Hidemasa Katsumi, and Akira Yamamoto

Fosphenytoin Alleviates Herpes Simplex Virus Infection-Induced Provoked and Spontaneous Pain-Like Behaviors in Mice

Ichiro Takasaki, Ryota Nagashima, Takahiro Ueda, Tomoki Ogata, Arata Inoue, Kimiyasu Shiraki, Yoshimi Kitada, and Saori Arai

Development of a Novel Gastric Process Simulation Model: The Successful Assessment of Bioequivalence and Bioinequivalence of a Biopharmaceutics Classification System Class II Weak Acid Drug

Naoki Zenda, Tatsuaki Tagami, and Tetsuya Ozeki

Notes

Trends in Investigator-Initiated Clinical Studies at a University Hospital after Enforcement of the 2018 Clinical Trials Act in Japan

Yasutaka Sato, Satoshi Sakaguchi, Kenshi Takechi, Masayuki Chuma, Kenta Yagi, Chikako Kane, Mitsuhiro Goda, Hirofumi Hamano, Yuki Aoe, Hiroshi Nokihara, Yoshiaki Kubo, Ichiro Hashimoto, and Hiroaki Yanagawa

In Vitro Production of Optically Active Octahydrocurcumin by Human Intestinal Bacterium

Toshio Niwa, Shin-ichiro Yokoyama, Mika Mochizuki, and Toshihiko Osawa