Sent Date: February 1, 2022

The latest issue of Chem. Pharm. Bull. (CPB)

Vol. 70 No. 2

Review

Protein Chemical Modification Using Highly Reactive Species and Spatial Control of Catalytic Reactions

Shinichi Sato

Communication to the Editor

μ-Oxo-Hypervalent-Iodine-Catalyzed Oxidative C-H Amination for Synthesis of Benzolactam Derivatives

Hirotaka Sasa, Koyo Mori, Kotaro Kikushima, Yasuyuki Kita, and Toshifumi Dohi

Regular Articles

Synthesis of 4,4-Disubstituted 3,4-Dihydropyrimidin-2(1H)-ones and -thiones, the Corresponding Products of Biginelli Reaction Using Ketone, and Their Antiproliferative Effect on HL-60 Cells

Yoshio Nishimura, Hidetomo Kikuchi, Takanori Kubo, Rie Arai, Yuki Toguchi, Bo Yuan, Katsuyoshi Sunaga, and Hidetsura Cho

Enthalpy-Entropy Compensation in the Structure-Dependent Effect of Nonsteroidal Anti-inflammatory Drugs on the Aqueous Solubility of Diltiazem

Takatoshi Kinoshita, Chihiro Tsunoda, Satoru Goto, Kanji Hasegawa, Hitoshi Chatani, Momoko Fujita, Hikaru Kataoka, Yuta Katahara, Yohsuke Shimada, Yuta Otsuka, Kazushi Komatsu, and Hiroshi Terada

Surface Plasmon Resonance of Two-Dimensional Gold Colloidal Crystals Formed on Gold Plates

Yurina Aoyama, Akiko Toyotama, Tohru Okuzono, Naohide Hirashima, Hiroki Imai, Fumio Uchida, Yoshihiro Takiguchi, and Junpei Yamanaka

Simultaneous Determination of Active Pharmaceutical Ingredients and Water-Soluble Polymers: Analysis of Dissolution Profiles from Sustained-Release Formulations and Mechanisms Involved

Mariko Kimoto, Toshiyasu Sakane, Hidemasa Katsumi, and Akira Yamamoto

Development of Scaled-Up Synthetic Method for Retinoid X Receptor Agonist NEt-3IB Contributing to Sustainable Development Goals

Yuta Takamura, Ken-ichi Morishita, Shota Kikuzawa, Masaki Watanabe, and Hiroki Kakuta

Chemical Synthesis and Evaluation of Exopolysaccharide Fragments Produced by Leuconostoc mesenteroides Strain NTM048

Shinsuke Inuki, Hitomi Tabuchi, Chiaki Matsuzaki, Yasunori Yonejima, Keiko Hisa, Ikuo Kimura, Kenji Yamamoto, and Hiroaki Ohno

Characterization of the Salt and Free Base of Active Pharmaceutical Ingredients Based on NMR Relaxometry Measured by Time Domain NMR

Yuya Chiba, Kotaro Okada, Yoshihiro Hayashi, Kok Hoong Leong, Shungo Kumada, and Yoshinori Onuki

Notes

LC-MS/MS Assay for the Measurement of Cannabidiol Profiling in CBD Oil from Japanese Market and Application for Convertible Tetrahydrocannabinol in Acetic Acid Condition

Shiori Takashina, Miki Takahashi, Koji Morimoto, and Koichi Inoue

Chemical Components in Hedera rhombea Leaves and Their Cytotoxicity

Akihito Yokosuka, Tatsuya Shimomura, Shohei Yokogawa, Airi Oguro, Katsunori Miyake, and Yoshihiro Mimaki

Bromine K-Edge X-Ray Absorption Near-Edge Structure Analysis on Hydrobromide-Salt Crystals and the Solid Dispersion of Active Pharmaceutical Ingredients

Hironori Suzuki, Asumi Tomita, Masataka Ito, and Shuji Noguchi

Secorubenine, a Monoterpenoid Indole Alkaloid Glycoside from Adina rubescens: Isolation, Structure Elucidation, and Enantioselective Total Synthesis

Nanako Nakashima, Jukiya Sakamoto, Kenta Rakumitsu, Mariko Kitajima, Lia Dewi Juliawaty, and Hayato Ishikawa