Sent Date: January 1, 2022

The latest issue of Biol. Pharm. Bull. (BPB)

Vol. 45 No. 1

Reviews

Reciprocal Relationship between Ca²⁺ Signaling and Ca²⁺-Gated Ion Channels as a Potential Target for Drug Discovery

Yuji Imaizumi

Application of Reverse Docking in the Research of Small Molecule Drugs and Traditional Chinese Medicine

Hongxu Wang, Huiqin He, Tingting Zhang, and Jingwei Jiang

Regular Articles

Coadministration of Curcumin and Hydromorphone Hydrochloride Alleviates Postoperative Pain in Rats

Yihan Wang, Yang Liu, Jieting Liu, Min Wang, and Yingbin Wang

Imatinib Mesylate Exerted Antitumor Effect by Promoting Infiltration of Effector T Cells in Tumor

Aya Hirata, Eri Sawai, Marina Henmi, Chihiro Shibasaki, Yukihiro Mizoguchi, Kenta Narumi, and Kazunori Aoki

Efficacy and Safety of Propranolol Gel for Infantile Hemangioma: A Randomized, Double-Blind Study

Naoaki Rikihisa, Hirokazu Takatsuka, Takaaki Suzuki, Yuki Shiko, Yohei Kawasaki, Michiko Hanawa, Itsuko Ishii, and Nobuyuki Mitsukawa

Salvia miltiorrhiza Prevents Methylglyoxal-Induced Glucotoxicity via the Regulation of Apoptosis-Related Pathways and the Glyoxalase System in Human Umbilical Vein Endothelial Cells

Jae Sung Kim, Jae Hyuk Lee, Seong Min Hong, Kyo Hee Cho, and Sun Yeou Kim

Gambogenic Acid Inhibits Basal Autophagy of Drug-Resistant Hepatoma Cells and Improves Its Sensitivity to Adriamycin

Meng Wang, Fan Zhan, Hui Cheng, and Qinglin Li

Effect of Ginsenoside Rb2 on a Myocardial Cell Model of Coronary Heart Disease through Nrf2/HO-1 Signaling Pathway

Yuning Li and Wenhua Zhang

Indomethacin, a Non-steroidal Anti-inflammatory Drug, Induces Skin Dryness via PPARγ in Mice

Kiyoko Maruyama, Kenji Goto, Keiichi Hiramoto, Shota Tanaka, and Kazuya Ooi

LncRNA Snhg5 Attenuates Status Epilepticus Induced Inflammation through Regulating NF-κΒ Signaling Pathway

Ming Wang, Yangmei Xie, Yiye Shao, and Yinghui Chen

Radiosynthesis and in Vivo and ex Vivo Evaluation of Isomeric [¹¹C]methoxy Analogs of Nimesulide as Brain Cyclooxygenase-2-Targeted Imaging Agents

Yumi Yamamoto, Tetsuro Tago, Jun Toyohara, Yohei Saito, and Fumihiko Yamamoto

Impact of Gut Microbiota on the Pharmacokinetics of Glycyrrhizic Acid in Yokukansan, a Kampo Medicine

Tomoaki Ishida, Kohei Jobu, Kei Kawada, Shumpei Morisawa, Tetsushi Kawazoe, Hisashi Shiraishi, Hiroko Fujita, Satomi Nishimura, Hitomi Kanno, Mitsue Nishiyama, Kazuo Ogawa, Yasuyo Morita, Kazuhiro Hanazaki, and Mitsuhiko Miyamura

A Genome-Wide Association Study Predicts the Onset of Dysgeusia Due to Anti-cancer Drug Treatment

Minori Takei, Naoto Okada, Shingen Nakamura, Kumiko Kagawa, Shiro Fujii, Hirokazu Miki, Keisuke Ishizawa, Masahiro Abe, and Youichi Sato

Medication Wastage in a University Hospital in Japan

Tetsuya Ueki, Emiko Sanematsu, Sara Kawano, Yuriko Nakamura, Naoko Kawamichi, Yoshitake Shinohara, Kazuhiro Yatera, and Fumihiro Tanaka

Machine Learning Prediction of the Three Main Input Parameters of a Simplified Physiologically Based Pharmacokinetic Model Subsequently Used to Generate Time-Dependent Plasma Concentration Data in Humans after Oral Doses of 212 Disparate Chemicals

Yusuke Kamiya, Kentaro Handa, Tomonori Miura, Junya Ohori, Airi Kato, Makiko Shimizu, Masato Kitajima, and Hiroshi Yamazaki

Using Bio-Layer Interferometry to Evaluate Anti-PEG Antibody-Mediated Complement Activation

Mahmoud Mostafa, Nehal E. Elsadek, Sherif E. Emam, Hidenori Ando, Taro Shimizu, Hamdy Abdelkader, Yu Ishima, Usama Farghaly Aly, Hatem A. Sarhan, and Tatsuhiro Ishida

External Evaluation of a Bayesian Warfarin Dose Optimization Based on a Kinetic-Pharmacodynamic Model

Takahiko Aoyama, Toshinori Hirai, Yasuhiro Tsuji, Aoi Miyamoto, Toshimasa Itoh, Takuya Iwamoto, and Yoshiaki Matsumoto

Neuroprotective Effects of Tetrahydroxystilbene Glucoside against Rotenone-Induced Toxicity in PC12 Cells

Ruoqiu Fu, Haiyan Xing, Xianfeng Wang, Yao Liu, Bin Li, Lin Zhang, Ziwei Li, Dongyu Duan, and Jianhong Chen

Note

Directional Drug Transport through Membrane-Supported Monolayers of Human Liver-Derived Cell Lines

Kenta Mizoi, Misako Kobayashi, Arisa Mashimo, Eiko Matsumoto, Norio Masuda, Manabu Itoh, Toshiya Ueno, Hidehisa Tachiki, Seiichi Ishida, and Takuo Ogihara