Chem. Pharm. Bull. Vol. 70 No. 11

Biological and Pharmaceutical Bulletin

Development of Naturally Inspired Peptide and Protein Chemistry
pp. 748-764


Graphical Abstracts


Development of Naturally Inspired Peptide and Protein Chemistry

Akira Otaka


Communication to the Editor

Lewis Acid-Conjugated Pyrene Photoredox Catalyst Promoting the Addition Reaction of α-Silyl Amines with Benzalmalononitriles

Yuri Katayama, Harunobu Mitsunuma, and Motomu Kanai


Regular Articles

Synthesis and Evaluation of a Paclitaxel-Binding Tripeptide Micelle for Lung Cancer Therapy

Jie Gao, Yijiang Jia, Taledaohan Ayijiang, Tuohan MarMar, Xi Hu, Li Li, Yuanming Li, and Yuji Wang


Structural, Theoretical Analysis, and Molecular Docking of Two Benzamide Isomers. Halogen Bonding and Its Role in the Diverse Ways of Coupling with Protein Residues

Rodolfo Moreno-Fuquen, Esteban García-Torres, Kevin Arango-Daraviña, and Javier Ellena


Cyclosporin A Inhibits the Activation of Membrane-Bound Guanylate Cyclase GC-A of Atrial Natriuretic Factor via NAD(P)H Oxidase

Chuan-San Fan, Ying-Shan Chu, Jhih-Wen Hsu, Ya-Chi Chan, Chia-Lin Wu, and Chung-Ho Chang


Development of Highly Sensitive Method for Sugar Determination in Herbal Medicine; Application of Monosaccharides and Oligosaccharides in Japanese Angelica Root and Rehmannia Root

Xu Han, Hirokazu Ando, Yoshitomi Kudo, and Yohei Sasaki


Hepatoprotective Effects of Phloridzin against Isoniazid-Rifampicin Induced Liver Injury by Regulating CYP450 and Nrf2/HO-1 Pathway in Mice

Jiao Yang, Guorong Li, Xiaoai Bao, Yujie Suo, Hailong Xu, Ying Deng, Tianyan Feng, and Gaigai Deng


Effects of Substituting Disubstituted Amino Acids into the Amphipathic Cell Penetrating Peptide Pep-1

Takuma Kato, Hiroaki Numa, Mihoko Nakamachi, Akiko Asano, and Mitsunobu Doi



Cyclopsammocinamides A and B, Enantiomeric Cyclic Peptides of Cyclocinamide A, from the Marine Sponge Psammocinia sp.

Ahmed H. H. El-Desoky, Yuki Hitora, Keita Onodera, Yuji Ise, Fitje Losung, Remy E. P. Mangindaan, and Sachiko Tsukamoto


Synthesis of Acetogenin Analogs Comprising Pyrimidine Moieties Linked by Amine Bonds and Their Inhibitory Activity against Human Cancer Cell Lines

Hiroyuki Hosomi, Akinobu Akatsuka, Shingo Dan, Hiroki Iwasaki, Hisanori Nambu, and Naoto Kojima


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