Sent Date: August 1, 2022

The latest issue of Biol. Pharm. Bull. (BPB)

Vol. 45 No. 8

Review

Development of siRNA Delivery System by Lipid Nanoparticles Modified with Functional Materials for Cancer Treatment

Yu Sakurai

Current Topics - Emerging Roles of Lipid Mediators in Health Sciences

Foreword

Shuntaro Hara

Current Topics: Reviews

Prostacyclin Synthase as an Ambivalent Regulator of Inflammatory Reactions

Tsubasa Ochiai, Toshiya Honsawa, Yuka Sasaki, and Shuntaro Hara

Prostaglandin D₂ and F_2α as Regulators of Adipogenesis and Obesity

Ko Fujimori

Metabolic Regulation in Adipocytes by Prostanoid Receptors

Tomoaki Inazumi and Yukihiko Sugimoto

Polyunsaturated Fatty Acid-Derived Lipid Mediators That Regulate Epithelial Homeostasis

Tatsuro Naganuma, Nodoka Fujinami, and Makoto Arita

The Many Roles of Lysophospholipid Mediators and Japanese Contributions to This Field

Yugo Takagi, Shun Nishikado, Jumpei Omi, and Junken Aoki

Communication to the Editor

Purification of Emu IgY for Therapeutic and Diagnostic Use Based on Monoclonal Secondary Antibodies Specific to Emu IgY

Kouya Yamaki, Kiyoe Ohta, Norihiro Kobayashi, Izumi Morita, Yuki Kiguchi, Hiroyuki Oyama, Ken Ito, Asuka Nanbo, Hirozo Oh-oka, Yutaka Koyama, Yoshiki Kawata, Hirotaka Fujisawa, and Mitsuhiro Ohta

Regular Articles

Picropodophyllin Inhibits the Proliferation of Human Prostate Cancer DU145 and LNCaP Cells via ROS Production and PI3K/AKT Pathway Inhibition

Xuejie Zhu, Xiaojie Chen, Guoli Wang, Dan Lei, Xiaoyu Chen, Kehao Lin, Minjing Li, Haiyan Lin, Defang Li, and Qiusheng Zheng

Inhibitory Effect of Dextran Derivatives on Multidrug Resistance-Related Efflux Transporters in Vitro

Kaori Morimoto, Makoto Ishii, Yoshikazu Sugimoto, Takuo Ogihara, and Mikio Tomita

Selexipag Improves Lipopolysaccharide-Induced ARDS on C57BL/6 Mice by Modulating the cAMP/PKA and cAMP/Epac1 Signaling Pathways

Hongliu Chen, Ying Shen, Yi Liang, Ying Qiu, Meili Xu, and Chaoqian Li

Therapeutic Strategy for Rheumatoid Arthritis by Induction of Myeloid-Derived Suppressor Cells with High Suppressive Potential

Shohei Nakano, Norihisa Mikami, Mai Miyawaki, Saho Yamasaki, Shoko Miyamoto, Mayu Yamada, Tomoya Temma, Yousuke Nishi, Arata Nagaike, Seijun Sakae, Takuya Furusawa, Ryoji Kawakami, Takumi Tsuji, Takeyuki Kohno, and Yuya Yoshida

Phosphatidylserine-Specific Phospholipase A1 Alleviates Lipopolysaccharide-Induced Macrophage Inflammation by Inhibiting MAPKs Activation

Wei Zhang, Chao Liu, Mengmeng Wang, Zhizhou Yang, Jian Yang, Yi Ren, Liping Cao, Xiaoqin Han, Limin Huang, Zhaorui Sun, and Shinan Nie

Role of Nrf2 in Methotrexate-Induced Epithelial-Mesenchymal Transition in Alveolar A549 Cells

Masashi Kawami, Mikito Honda, Takuya Hara, Ryoko Yumoto, and Mikihisa Takano

Signal Detection of Acute Renal Failure Following the Use of SGLT-2 Inhibitors: Stratified Analysis and Time Trend Analysis in Japan and the United States

Yukari Katsuhara and Shunya Ikeda

Impact of Inflammation on Intra-individual Variation in Trough Voriconazole Concentration in Patients with Hematological Malignancies

Yu Maeda, Ryota Tanaka, Ryosuke Tatsuta, Kuniko Takano, Takehiro Hashimoto, Masao Ogata, Kazufumi Hiramatsu, and Hiroki Itoh

Pharmacists' Adherence Support System FollowNavi for Patients with Type 2 Diabetes

Shu Sekiya, Tatsunori Suzuki, Rei Tanaka, Shumpei Harigai, Konosuke Shimono, Susumu Ohura, Hajime Hashiba, and Yoshiaki Shikamura

Changes in Pharmacodynamic Parameters during Co-administration of 5-FU with Warfarin: A Retrospective Case Series

Jose Carlos S. Tayag, Takeo Ishii, Shun Kokuba, Tetsuo Hirata, Hideo Shiohira, and Katsunori Nakamura

Andrographolide/Phospholipid/Cyclodextrin Complex-Loaded Nanoemulsion: Preparation, Optimization, in Vitro and in Vivo Evaluation

Linghui Zou, Wenya Ding, Qiuyan Huang, Xu Yang, Jilang Li, Tianyan Huang, Zeyu Li, Si Lin, and Jianfang Feng

Regioselective Glucuronidation of Flavones at C5, C7, and C4′ Positions in Human Liver and Intestinal Microsomes: Comparison among Apigenin, Acacetin, and Genkwanin

Nobumitsu Hanioka, Toshiko Tanaka-Kagawa, Yoko Mori, Shinichi Ikushiro, Hideto Jinno, Susumu Ohkawara, and Takashi Isobe

Autism Spectrum Disorder Model Mice Induced by Prenatal Exposure to Valproic Acid Exhibit Enhanced Empathy-Like Behavior via Oxytocinergic Signaling

Kaito Takayama, Shota Tobori, Chihiro Andoh, Masashi Kakae, Masako Hagiwara, Kazuki Nagayasu, Hisashi Shirakawa, Yukio Ago, and Shuji Kaneko

A Chinese Medicine, Tokishakuyakusan, Increases Bovine Oviductal Tonus via G Protein-Coupled Estrogen Receptor 1

Sayaka Kubota, Yuki Yamamoto, and Koji Kimura

Trivariate Linear Regression and Machine Learning Prediction of Possible Roles of Efflux Transporters in Estimated Intestinal Permeability Values of 301 Disparate Chemicals

Makiko Shimizu, Riku Hayasaka, Yusuke Kamiya, and Hiroshi Yamazaki

Effects of NP-1815-PX, a P2X4 Receptor Antagonist, on Contractions in Guinea Pig Tracheal and Bronchial Smooth Muscles

Keisuke Obara, Rikako Inaba, Mirai Kawakita, Azusa Murata, Kento Yoshioka, and Yoshio Tanaka

Efficacy of a Pharmacist Team Clinical Medication Review in Older Adults: A Prospective and Retrospective Observational Study

Masakazu Hatano, Tomohiro Mizuno, Yuki Arakawa, Risa Inagaki, Arisa Kato, Haruna Matsuzaki, Fumihiro Mizokami, Takenao Koseki, and Shigeki Yamada

Nmu/Nms/Gpr176 Triple-Deficient Mice Show Enhanced Light-Resetting of Circadian Locomotor Activity

Yoshiaki Yamaguchi, Iori Murai, Momoko Takeda, Shotaro Doi, Takehito Seta, Reiko Hanada, Kenji Kangawa, Hitoshi Okamura, Takahito Miyake, and Masao Doi

Ibudilast Reduces IL-6 Levels and Ameliorates Symptoms in Lipopolysaccharide-Induced Sepsis Mice

Naoko Kadota, Akari Yoshida, Atsushi Sawamoto, Satoshi Okuyama, and Mitsunari Nakajima

Isoform-Specific Quantification of Human Bitter Taste Receptor Transcripts Using Real-Time PCR Analysis

Yoko Mori, Akira Aoki, Yoshinori Okamoto, Takashi Isobe, Susumu Ohkawara, Nobumitsu Hanioka, Toshiko Tanaka-Kagawa, and Hideto Jinno

Gamma-Glutamylcysteine Production Using Phytochelatin Synthase-Like Enzyme Derived from Nostoc sp. Covalently Immobilized on a Cellulose Carrier

Misa Muraoka, Moeka Ohno, Takuya Nakai, Hideyuki Matsuura, Kazuya Nagano, Masayoshi Arai, Yoshihiko Hirata, Hiroshi Uyama, and Kazumasa Hirata

Notes

Replication Study for the Association of Five SNPs Identified by GWAS and Trastuzumab-Induced Cardiotoxicity in Japanese and Singaporean Cohorts

Chihiro Udagawa, Sherwin Kuah, Tatsunori Shimoi, Ken Kato, Teruhiko Yoshida, Mari Hara Nakano, Arata Shimo, Yasuyuki Kojima, Reiko Yoshie, Koichiro Tsugawa, Taisei Mushiroda, Ern Yu Tan, and Hitoshi Zembutsu

Intracerebroventricular Administration of Dermorphin-Dynorphin Analogs Producing Antidepressant-Like Effects through Activation of μ₁- and κ-Opioid Receptors in Mice

Osamu Nakagawasai, Akihiro Ambo, Kohei Takahashi, Hiroshi Onogi, Yuki Nishimura, Myu Okubo, Wataru Nemoto, and Koichi Tan-No

Inhibition of Spred/Sprouty Expression in the Skin of a Contact Dermatitis-Like Model

Hiroyasu Sakai, Ken Sato, Koya Ito, Ikoi Kosugi, Miho Kiyama, Risako Kon, Nobutomo Ikarashi, Junzo Kamei, Yoshihiko Chiba, and Tomoo Hosoe