program145

17/55

S38 Understanding the Complexity of the Retina and Seminal ABSTRACT 16 Therapeutic Strategies S15-4 Medium-sized molecule drug discovery platform —case study of LUNA18’s drug discovery research— S38-1 Using MINFLUX microscopy to probe nanoscopic receptor organization of the mammalian cone photoreceptor synapse S38-2 Effect of retinal lamination disruption on retinal function in mice S38-3 The mechanism underlying pathological oscillation in the mouse retina S38-4 Mutation-independent targeted gene insertion therapeutics to treat autosomal dominant retinitis pigmentosa in mouse and primate systems 1. Ōmura Inst., Kitasato Univ. ○Minoru Tamiya1, Mikimasa Tanada1, Koji Takano1, Takuya Shiraishi1, Aya Chiyoda1, Toshiya Ito1, Kenichi Nomura1, Satoshi Hashimoto1, Ryuuichi Takeyama1, Tom 1. Chugai Pharmaceutical CO., LTD. ○Daiki Futagi1, Steven DeVries1 1. Dept. Ophthalmology, Northwestern Univ. ○Akiko Ueno1,2 1. Pharm., Ritsumeikan University, 2. Center for Systems Vision Science ○Sho Horie1, Konan Sakuta1, Keigo Tada2, Haruki Tokumoto1, Taketo Nishimoto1, Katsunori Kitano3,4,5, Masao Tachibana4, Chieko Koike4,5,6 1. Grad. Sch. Pharm., Ritsumeikan Univ., 2. Grad. Sch. ISE., Ritsumeikan Univ., 3. Col. ISE., Ritsumeikan Univ., 4. CSVS., Ritsumeikan Univ., 5. R-GIRO., Ritsumeikan Univ., 6. Col. Pharm., Ritsumeikan Univ. ○Akishi Onishi1,2,3,4 1. VCGT Inc., 2. Res. Org. Sci. Tech., Ritsumeikan Univ., 3. RIKEN BZP, 4. Kobe City Eye Hospital Research Center ABSTRACT ABSTRACT ABSTRACT ABSTRACT ABSTRACT