29P-pm216S Construction and optimization of screening system for high-precision Cas9 variants ○SHAHRAM AHMADI1, Komari Kubota2, Daisuke Matsumoto 1,2, Kiyomi Nigorikawa 1,2, Wataru Nomura 1,2 1. Grad. Sch. Biomed. and Health Sci., Hiroshima Univ. , 2. Sch. Pharm Sci., Hiroshima Univ. 29P-pm242S Cisplatin induces non-canonical activation of EphA2 through the MK2-RSK signaling pathway. ○Zhou Yaling1, Zhou Yue1, Yokoyama Satoru1, Horibe Sayo2, Sakurai Hiroaki1 1. Cancer Cell Biol., Grad. Sch. Pharm. Sci., Toyama Univ., 2. Kobe Pharm. Univ. 30P-pm207 Role of astrocyte-derived exosomes in hemin-induced neurotoxicity ○Hui-Ju Huang1, Cian-Huei Lin2, Yu-Li Lo3, Anya Maan-yuh Lin1,2,3,4 1. Dep. Medical Research, Taipei Veterans General Hospital, 2. Institute of Physiology, National Yang Ming Chiao Tung Univ., 3. Institute of Pharmacology, National Yang Ming Chiao Tung Univ., 4. Fac. Pharm. National Yang Ming Chiao Tung Univ. 30P-pm251 Melatonin synergizes with Olaparib and promotes drug sensitivity via suppressing cancer-associated fibroblast (CAF) activation ○Yi Wen Lai1,2, Cheng Wei Lin1,2 1. Sch. Medicine, Coll. Med., Taipei Medical Univ.,, 2. Sch. Medicine, Coll. Med., Taipei Medical Univ. 29P-am262 Pharmacogenomic biomarkers for chemotherapy responsiveness identified by integrated transcriptomic analyses ○Varalee Yodsurang1, Wathunya Hawhan1, Krittin Pitinanon1, Chotiphuk Kusalasaiyanon1, Pasrawin Taechawattananant2 1. Fac. Pharm. Sci., Chulalongkorn Univ., 2. Fac. Pharm. Sci., Chulalongkorn Univ. 29P-am263 The epidermal growth factor receptor inhibitor epertinib reverses P-glycoprotein-mediated multidrug resistance in cancer cell lines Yen-Ching Li1, Bing-Huan Lin1, Megumi Murakami2, Suresh V Ambudkar2, ○Chung-Pu Wu1,3,4,5 1. Coll. Med., Chang Gung Univ., 2. Center for Cancer Research, National Cancer Institute, NIH, 3. Coll. Med., Chang Gung Univ., 4. Dep. Obstetrics and Gynecology, Taipei Chang Gung Memorial Hosp., 5. Molecular Medicine Research Center, Coll. Med., Chang Gung Univ. ABSTRACT ABSTRACT ABSTRACT ABSTRACT ABSTRACT ABSTRACT
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