S-40 Discovery and Development of Bioactive Natural Products for Drug Exporing – Frontier of Chemical Biology Researches – S40-1 Target identification of bioactive small molecules S40-2 Search for anti-tuberculosis agent based on enviroment of infected region and identification of its target molecule S40-3 Natural product-based bioactive molecules S40-4 Engineered biosynthesis of medicinal natural products S40-5 System Chemotherapy: Approach toward Overcoming Multifactorial Deseases from Medicinal Chemistry