S-10 Advanced Approaches to Anti-aging – Use of aging model animals – S10-1 Anti-aging research using klotho mouse S10-2 Anti-aging studies on the senescence accelerated mouse (SAM) strains S10-3 Model mice for tissue-specific deletion of the manganese superoxide dismutase (Mn-SOD) gene S10-4 Anti-aging research that uses SMP30/GNL knockout mouse S10-5 Analysis of aging-related oxidative stress status in normal aging animals and development of anti-aging interventions S10-6 Overview : Application of animal models for anti-aging