S-41 Biology-oriented Chemistry in Pharmaceutical Sciences -Exploring "the function of biological system" by Chemical Biology-   S41-1. Site-nonselective introduction of bioactive small molecules on solid support: A paradigm shift in chemical genetic research?   S41-2. Development of Bridged Nucleic Acids for Gene Regulation and Analysis   S41-3. Chemical Approaches toward Target Identification of Antitumor Natural Product Pladienolide   S41-4. Molecular Anatomy of the Matrix Proteins   S41-5. Rational design and development of fluorescence probes and their application to cellular and cancer imaging   S41-6. A New Aspect of Microtubule Targeting Agents as Anti-Cancer Drugs