S-31 Virtual Screening Based on Protein-Ligand Interactions   S31-1. Virtual Screening by Docking Method   S31-2. Possibility and Question of Drug Discovery Based on Structure-Based Drug Design   S31-3. Interface between Docking study and Bioinformatics   S31-4. Receptor-Ligand Docking Simulation for Membrane Proteins   S31-5. Drug Discovery Directly from Protein 3D Structures