SS03 Current Trends of Theoretical and Medicinal Chemistry SS03-1 ONIOM theoretical studies of chemical reactions in protein and organometallic catalytic reactions SS03-2 Structure Modeling and Binding Energy Calculation by Fragment Molecular Orbital Method for Protein-Ligand Complex SS03-3 Signal Transduction and Transcription Regulation based on Molecular Structure SS03-4 The case study to logical design and synthesis of nuclear receptor ligands; PPAR agonists as an example SS03-5 Nuclear receptor and protease as a drug target SS03-6 Molecular simulations on protein-complex and drug design